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A DNA fragment of $5000bp$ needs to be isolated from E.coli (genome size $4\times10^3kb$) genomic library.

The number of clones to represent this fragment in genomic library with a probability of $95\%$ are

  1. $5.9\times10^3$
  2. $4.5\times10^3$
  3. $3.6\times10^3$
  4. $2.4\times10^3$
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