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Match the items in $\text{Group I}$ with $\text{Group II}$

$\begin{array}{|l|l|l|l|} \hline & \text{Group I} & & \text{Group II} \\ \hline P. & \text{Receptor tyrosine kinase} & 1. & \text{ Inactivation of G-proteins} \\ \hline Q. & \text{Cyclic GMP (cGMP)} & 2. & \text{Reception of insulin signal} \\ \hline R. & \text{GTPase activating protein (GAP)} & 3.  & \text{Thyroid hormone} \\ \hline S. & \text{Nuclear receptor} & 4. & \text{Receptor huanylyl cyclase} \\ \hline \end{array}$

  1. $\text{P-1, Q-3, R-4, S-2}$
  2. $\text{P-2, Q-4, R-3, S-1}$
  3. $\text{P-3, Q-1, R-4, S-2}$
  4. $\text{P-2, Q-4, R-1, S-3}$
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