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In animal cells, the endogenously produced $\text{miRNAs}$ silence gene expression by

  1. base pairing with the $3’$-untranslated region of specific $\text{mRNAs}$
  2. blocking $\text{mRNA}$ synthesis
  3. binding to the operator site
  4. base pairing with the $3’$ region of specific $\text{rRNAs}$
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