Recent questions and answers in Molecular Biology and Genetics:

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In nitrogen fixation, to reduce nitrogen to ammonia, which one of the following shows the correct order of electron flow?Ferredoxin → reductase → nitrogenaseNADH → reduct...
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For monoclonal antibody production, hypoxanthine $\_\_\_\_$.allows DNA synthesis in the absence of de novo dTMP synthesisallows purine synthesis in cells containing HGPRT...
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Which one of the following antibiotics blocks protein chain elongation by preventing the action of peptidyl transferase?BleomycinRifampicinChloramphenicolTetracycline
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The RNA primer synthesized during bacterial DNA replication is removed by $\_\_\_\_$.DNA gyraseDNA Polymerase $\text{I}$PrimaseDNA Polymerase $\text{III}$
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Match the biomolecules in Column $\text{I}$ with their function given in Column $\text{II}$\[\begin{array}{|l|l|}\hline\text{Column I} & \text{Column II} \\\hline\text{P....
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Messenger $\text{RNAs (mRNAs)}$ translate to generate polypeptides and the translation terminates at the $\text{UGA, UAG}$ or $\text{UAA}$ stop codons. The $\text{AGA}$ c...
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The RNA sequence below depicts the part of a $330$ nucleotides long $\text{mRNA}$ and it encodes the $\text{C}$-terminal portion of a protein.$5^{\prime}-\ldots \ldots$ $...
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Which of the following is/are posttranslational modification(s) involved in epigenetic control of gene expression?Arginine methylationLysine acetylationCytosine methylati...
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​​​​Which one of the following is true for piRNAs?piRNAs silence transposable elements in germ cellspiRNA is the abbreviation of $P$-element interacting RNApiRNAs modify ...
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​​​​Which of the following enzymes is/are involved in the biogenesis of miRNA?DroshaCas$9$XRCC$4$Dicer
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The contour length of a B-DNA molecule that encodes a bacterial protein of $33 \: \text{kDa}$ is $\_\_\_\_$ $\mathrm{ nm}$.Consider the average molecular weight of an ami...
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​​​​​An octapeptide composed of these $L$-amino acids - Lys, Thr, Ser, Met, Arg, Trp, Tyr, Glu - was subjected to analyses with the following outcomes:$\text{P}$. The N-t...
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Correctly match the Enzyme with its respective Function.\begin{array}{|l|l|}\hline \textbf{ Enzyme } & \textbf{ Function } \\\hline \text{P. Gyrase} & 1. \text{Removes a ...
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​​​​Which of the following statements about initiation of DNA replication in eukaryotes is/are true?DNA replication is initiated at the origin of replication licensed by ...
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​​​​Which of the following proteins is/are involved in intraflagellar transport?MicrotubulesMyosinActinKinesin
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​​​​Which of the following statements is/are true about telomerase?Telomerase has $5^{\prime}-3^{\prime}$ DNA-dependent DNA polymerisation activityTelomerase has $5^{\pri...
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Co-translational translocation of proteins is observed in $\_\_\_\_\_\_\_$.endoplasmic reticulumGolgi complexmitochondriaperoxisomes
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A cultured skin fibroblast cell of a goat ' $\mathrm{P}$ ' was fused with an enucleated ovum of a goat ' $\mathrm{Q}$ '. The resultant activated early embryo was then tra...
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An element that is present in a nucleotide but not in a nucleoside is $\_\_\_\_\_\_\_$carbonnitrogenoxygenphosphorous
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If a denatured protein of human origin is injected into a rabbit, antibodies generated will recognize the $\_\_\_\_\_\_$ structure of the protein.primarysecondarytertiary...
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All pseudogenes DO NOT code for a $\_\_\_\_\_\_\_$.protein with original functionprotein with altered functionRNA with coding sequenceRNA with regulatory function
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Match the item (Column I) with its corresponding use (Column II).\begin{array}{|c|c|c|}\hline \text{Column I} & \text{Column II} \\\hline \text{P. Glutamine} & 1. \text{D...
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Match the genetic disorder (Column I) with its molecular basis (Column II).\begin{array}{|c|c|c|}\hline \text{Column I} & \text{Column II} \\\hline \text{P. Sickle-cell a...
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Which of the following statements regarding the below mentioned mRNA sequence is/are TRUE?$5'-\text{UGAUGAGCCUUAACCGGGAACGAAUUUAAG}-3'$It contains nine codons in the read...
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Which of the following conditions induce(s) the expression of $\beta$-galactosidase gene in the lac operon?Absence of glucoseAbsence of lactosePresence of glucosePresence...
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Eukaryotic transcription is carried out by DNA-dependent RNA polymeraseDNA-dependent DNA polymeraseRNA-dependent DNA polymeraseRNA-dependent RNA polymerase
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Acetylcholine released by the parasympathetic nerves has which one of the following functions in the heart pacemaker cells?It binds to $\text{GPCR}$ and activates $\text{...
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Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $[\mathrm{r}]$.Assertion $[\mathrm{a}]$: In multicellular organisms, cells o...
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C-value paradox refers tothe lack of correlation between genome size and genetic complexity of an organismthe presence of genetic sequences that propagate themselves with...
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Intracellular proteins are targeted for proteolytic degradation in proteasomes upon conjugation with ubiquitinintegrinpeptidasecalreticulin
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Match the types of RNA in Group I with their corresponding function in Group II.Group IGroup IIP. mRNA1. Serves as adaptors between mRNA and amino acids during protein sy...
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The event(s) that lead(s) to inactivation of tumor suppressor genes in cancer cells is(are)gene amplificationpromoter methylationloss of heterozygosityhistone acetylation
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Methylation of $\mathrm{CpG}$ islands near the promoter of a gene can inhibit transcription bypreventing RNA polymerase bindingfacilitating repressor bindingfacilitating ...
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Which of the following statement(s) is(are) TRUE about induced pluripotent stem cells?They can self-renewThey require specific signals to maintain their stemnessThey cann...
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DNA sample collected from an unidentified bacterial species $(Y)$ contains $13 \%$ of adenine. The $G+C$ content (in percentage) of $Y$ is ____________.
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The type of nucleic acid present in $\lambda$-phage isDouble stranded $\text{DNA}$Single stranded circular $\text{DNA}$Single stranded $\text{DNA}$Single stranded $\text{...
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In animal cells, the endogenously produced $\text{miRNAs}$ silence gene expression bybase pairing with the $3’$-untranslated region of specific $\text{mRNAs}$blocking $\t...
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Which of the following are CORRECT about protein structure?Secondary structure is formed by a repeating pattern of interactions among the polypeptide backbone atomsTertia...
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The enzymes involved in ubiquitinylation of cell-cycle proteins are$\text{E}_{1}$ and $\text{E}_{2}$ Only$\text{E}_{1}$ and $\text{E}_{3}$ Only$\text{E}_{1}$ and $\text{E...
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Adenine can undergo a spontaneous change to hypoxanthine in a cell, leading to a $\text{DNA}$ base pair mismatch. The $\text{CORRECT}$ combination of enzymes that are inv...
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