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81
GATE BT 2023 | Question: 40
E. coli cultivated at $298 \mathrm{~K}$ uptakes an uncharged compound (A) by passive diffusion. The intracellular and extracellular concentrations of $\mathrm{A}$ are $0.001 \mathrm{M}$ and $0.1 \mathrm{M}$, respectively. If the value of the ... $\mathrm{A}$ (rounded off to two decimal places) is ______________.
E. coli cultivated at $298 \mathrm{~K}$ uptakes an uncharged compound (A) by passive diffusion. The intracellular and extracellular concentrations of $\mathrm{A}$ are $0...
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82
GATE BT 2023 | Question: 39
Aqueous two-phase extraction is used to recover } \alpha \text {-amylase from a solution. A polypropylene glycol-dextran mixture is added and the solution separates into upper and lower phases. The partition coefficient is $4.0$ and the ratio of upper ... volume is $5.0$. The enzyme recovery or yield (in percentage, rounded off to the nearest integer) is ______________.
Aqueous two-phase extraction is used to recover } \alpha \text {-amylase from a solution. A polypropylene glycol-dextran mixture is added and the solution separates into ...
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83
GATE BT 2023 | Question: 10
The correct sequence of events during bacteriophage infection of a bacterial cell is landing $\rightarrow$ attachment $\rightarrow$ tail contraction $\rightarrow$ penetration and unplugging $\rightarrow$ DNA ejection attachment $\rightarrow$ ... $\rightarrow$ tail contraction $\rightarrow$ landing $\rightarrow$ penetration and unplugging $\rightarrow$ DNA ejection
The correct sequence of events during bacteriophage infection of a bacterial cell islanding $\rightarrow$ attachment $\rightarrow$ tail contraction $\rightarrow$ penetrat...
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84
GATE BT 2023 | Question: 3
Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $[\mathrm{r}]$. Assertion $[\mathrm{a}]$: In multicellular organisms, cells of different lineages have different gene expression profiles. Reason $[\mathrm{r}]$: Alternative splicing ... not the correct reason for $[\mathrm{a}]$ $[\mathrm{a}]$ is true but $[\mathrm{r}]$ is false
Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $[\mathrm{r}]$.Assertion $[\mathrm{a}]$: In multicellular organisms, cells o...
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85
GATE BT 2023 | Question: 20
Fabry disease in humans is a X-linked disease. The probability (in percentage) for a phenotypically normal father and a carrier mother to have a son with Fabry disease is _________.
Fabry disease in humans is a X-linked disease. The probability (in percentage) for a phenotypically normal father and a carrier mother to have a son with Fabry disease is...
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86
GATE BT 2023 | Question: 47
A protein has three identical sites arranged at the vertices of an equilateral triangle. If one site is filled with a dye (donor), the measured quantum yield $\left(\phi_{D}\right)$ is $0.5$. Filling one site with a donor dye and a ... of one site filled with donor and the other two sites filled with acceptor dye (rounded off to three decimal places) is _____________.
A protein has three identical sites arranged at the vertices of an equilateral triangle. If one site is filled with a dye (donor), the measured quantum yield $\left(\phi_...
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87
GATE BT 2023 | Question: 52
The values of the consistency index ' $K$ ' and the flow behavior index ' $n$ ' of a dilatant fluid are 0.415 (in CGS units) and $1.23$, respectively. The value of the apparent viscosity (in $g . \mathrm{cm}^{-1} . \mathrm{s}^{-1}$ ) of this fluid at a shear rate of $60 \mathrm{~s}^{-1}$ (rounded off to the nearest integer) is _____________.
The values of the consistency index ' $K$ ' and the flow behavior index ' $n$ ' of a dilatant fluid are 0.415 (in CGS units) and $1.23$, respectively. The value of the ap...
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88
GATE BT 2023 | Question: 46
If $1000 \mathrm{bp}$ of a double-helical DNA weighs $1 \times 10^{-18} \mathrm{gm}$ and distance between two $\mathrm{bp}$ is $0.34 \mathrm{~nm}$, the total amount of DNA (in mg, rounded off to one decimal place) required to stretch from Earth to Moon (assuming the distance between Earth and Moon to be $3,74,000 \mathrm{~km}$ ) is ______________.
If $1000 \mathrm{bp}$ of a double-helical DNA weighs $1 \times 10^{-18} \mathrm{gm}$ and distance between two $\mathrm{bp}$ is $0.34 \mathrm{~nm}$, the total amount of DN...
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89
GATE BT 2023 | Question: 51
Ten playing cards numbered $1,2,3, \ldots, 10$ are placed face down on a table. One card is drawn at random, its number recorded, and then replaced face down. A card is drawn again at random. The probability that the number on the second draw is greater than the number on the first draw (rounded off to two decimal places) is ___________.
Ten playing cards numbered $1,2,3, \ldots, 10$ are placed face down on a table. One card is drawn at random, its number recorded, and then replaced face down. A card is d...
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90
GATE BT 2023 | Question: 53
An evaporator is insulated using glass wool material of $0.15 \mathrm{~m}$ thickness. The inner most surface and the outer surface of the insulation are at $700{ }^{\circ} \mathrm{C}$ and $80^{\circ} \mathrm{C}$, respectively. The mean thermal ... in $W$ ) through $1.2 \mathrm{~m}^2$ of the evaporator wall surface (rounded off to the nearest integer) is ______________.
An evaporator is insulated using glass wool material of $0.15 \mathrm{~m}$ thickness. The inner most surface and the outer surface of the insulation are at $700{ }^{\circ...
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91
GATE BT 2023 | Question: 38
E. coli is cultivated in a chemostat operated at a dilution rate of $0.2 h^{-1}$. The values of biomass yield due to oxygen consumption and the steady state biomass concentration are $0.2 g \cdot g^{-1}$ and $10 g \cdot L^{-1}$, respectively. The oxygen transfer rate (in $g \cdot L^{-1} \cdot h^{-1}$) is ______________.
E. coli is cultivated in a chemostat operated at a dilution rate of $0.2 h^{-1}$. The values of biomass yield due to oxygen consumption and the steady state biomass conce...
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92
GATE BT 2023 | Question: 7
Dendritic cells are involved in cross-presentation of antigens. Which of the following protein(s) is(are) required for cross-presentation? P. Basic leucine zipper ATF-like transcription factor $3$ (BATF3) Q. Membrane associated ring-CH-type finger $1$ (MARCH-1) R. Solute carrier ... $\mathrm{R}$ only $\mathrm{P}, \mathrm{Q}$ and $\mathrm{R}$ only $\text{S}$ only
Dendritic cells are involved in cross-presentation of antigens. Which of the following protein(s) is(are) required for cross-presentation?P. Basic leucine zipper ATF-like...
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93
GATE BT 2023 | Question: 54
A proportional controller is used to control the temperature of an autoclave from $60^{\circ} \mathrm{C}$ to $130^{\circ} \mathrm{C}$. If the proportional band setting of the controller is $25 \%$, the proportional gain value is ___________.
A proportional controller is used to control the temperature of an autoclave from $60^{\circ} \mathrm{C}$ to $130^{\circ} \mathrm{C}$. If the proportional band setting of...
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94
GATE BT 2023 | GA Question: 6
Human beings are one among many creatures that inhabit an imagined world. In this imagined world, some creatures are cruel. If in this imagined world, it is given that the statement "Some human beings are not cruel creatures" is FALSE, then which of the following set of statement( ... $\text{(i)}$ and $\text{(ii)}$ $\text{(i), (ii)}$ and $\text{(iii)}$
Human beings are one among many creatures that inhabit an imagined world. In this imagined world, some creatures are cruel. If in this imagined world, it is given that th...
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95
GATE BT 2023 | Question: 13
In hybridoma technology, which one of the following enzymes is absent in the myeloma cells that are used for monoclonal antibody production? Hypoxanthine-guanine phosphoribosyltransferase Alanine aminotransferase Triose phosphate isomerase Glycosyltransferase
In hybridoma technology, which one of the following enzymes is absent in the myeloma cells that are used for monoclonal antibody production?Hypoxanthine-guanine phosphori...
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96
GATE BT 2023 | Question: 44
An enzyme (E) catalyzes the biochemical reaction $A \rightarrow B$ with $k_{c a t}$ equal to $500 s^{-1}$. If the initial reaction velocity $\left(V_{0}\right)$ is $10 \mu M . s^{-1}$ at the total enzyme concentration $\left[E_{t}\right]$ of $30 n M$ and substrate concentration $[\mathrm{A}]$ of $40 \mu M$, the value of $K_{m}($ in $\mu M)$ is ______________.
An enzyme (E) catalyzes the biochemical reaction $A \rightarrow B$ with $k_{c a t}$ equal to $500 s^{-1}$. If the initial reaction velocity $\left(V_{0}\right)$ is $10 \m...
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GATE BT 2023 | Question: 16
Which one of the following programs is used for finding distantly related (or remote) protein homologs? BLASTN BLASTX PSI-BLAST TBLASTX
Which one of the following programs is used for finding distantly related (or remote) protein homologs?BLASTNBLASTXPSI-BLASTTBLASTX
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98
GATE BT 2023 | Question: 4
Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $\text{[r]}$. Assertion $\text{[a]}$: Chromosome mutations can change the structure of chromosomes. Reason $\text{[r]}$ : All chromosome mutations arise due to nondisjunction of ... $[\mathrm{r}]$ are true but $[\mathrm{r}]$ is not the correct reason for $\text{[a]}$
Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $\text{[r]}$.Assertion $\text{[a]}$: Chromosome mutations can change the str...
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99
GATE BT 2023 | Question: 26
Match the immune tolerance mechanisms in Group I with their respective outcomes in Group II. Group I Group II P. Anergy 1. Elimination of activated T-cells after antigen clearance Q. Activation-induced cell death 2. Inhibition of auto-reactive T-cells at periphery R. Receptor editing 3. Unresponsiveness to ... $\text{P-3, Q-4, R-2, S-1}$ $\text{P-3, Q-2, R-4, S-1}$
Match the immune tolerance mechanisms in Group I with their respective outcomes in Group II.Group IGroup IIP. Anergy1. Elimination of activated T-cells after antigen clea...
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GATE BT 2023 | Question: 43
The following schematic diagram shows a chemostat with cell recycle where $\mathrm{F}_0$ and $\mathrm{F}_{\mathrm{r}}$ are the volumetric flow rates (in $L \cdot h^{-1}$ ) of feed and recycle streams, respectively. $\mathrm{X}_1, \mathrm{X}_0$ ... $\mathrm{X}$ (in $g \cdot L^{-1}$, rounded off to one decimal place) is ________________.
The following schematic diagram shows a chemostat with cell recyclewhere $\mathrm{F}_0$ and $\mathrm{F}_{\mathrm{r}}$ are the volumetric flow rates (in $L \cdot h^{-1}$ )...
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101
GATE BT 2023 | Question: 28
Match the virus in Group I with the type of genome it contains in Group II. Group I Group II P. T4 bacteriophage 1. dsRNA Q. SARS-CoV-2 2. ssDNA R. Pseudomonas phage $\phi 6$ 3. dsDNA S. $\phi X 174$ bacteriophage 4. ssRNA $\text{P-3, Q-4, R-1, S-2}$ $\text{P-2, Q-1, R-4, S-3}$ $\text{P-4, Q-3, R-2, S-1}$ $\text{P-1, Q-4, R-2, S-3}$
Match the virus in Group I with the type of genome it contains in Group II.Group IGroup IIP. T4 bacteriophage1. dsRNAQ. SARS-CoV-22. ssDNAR. Pseudomonas phage $\phi 6$3. ...
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102
GATE BT 2023 | Question: 9
Which one of the following statements is TRUE about leghemoglobin? It binds oxygen to protect nitrogenase It binds hemoglobin to protect oxygenase It binds oxygen to protect hydrogenase It binds oxygen to protect oxygenase
Which one of the following statements is TRUE about leghemoglobin?It binds oxygen to protect nitrogenaseIt binds hemoglobin to protect oxygenaseIt binds oxygen to protect...
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103
GATE BT 2023 | Question: 35
Which of the following vector(s) is(are) used to clone a DNA fragment of size $220 \mathrm{~kb}$? Bacterial artificial chromosome Yeast artificial chromosome Cosmids $\text{pUC19}$ plasmid
Which of the following vector(s) is(are) used to clone a DNA fragment of size $220 \mathrm{~kb}$?Bacterial artificial chromosomeYeast artificial chromosomeCosmids$\text{p...
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104
GATE BT 2023 | Question: 25
The distance between the two points of intersection of $x^{2}+y=7$ and $x+y=7$ (rounded off to two decimal places) is ___________.
The distance between the two points of intersection of $x^{2}+y=7$ and $x+y=7$ (rounded off to two decimal places) is ___________.
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105
GATE BT 2023 | Question: 34
Direct DNA transfer method(s) used for plant genetic engineering is(are) microparticle bombardment electroporation polyethylene glycol treatment Agrobacterium-mediated transformation
Direct DNA transfer method(s) used for plant genetic engineering is(are)microparticle bombardmentelectroporationpolyethylene glycol treatmentAgrobacterium-mediated transf...
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106
GATE BT 2023 | Question: 29
The event(s) that lead(s) to inactivation of tumor suppressor genes in cancer cells is(are) gene amplification promoter methylation loss of heterozygosity histone acetylation
The event(s) that lead(s) to inactivation of tumor suppressor genes in cancer cells is(are)gene amplificationpromoter methylationloss of heterozygosityhistone acetylation...
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107
GATE BT 2023 | Question: 21
The value of $\lim _{x \rightarrow 0}\left[\frac{\cos 2 x-\cos 4 x}{x^{2}}\right]$ is ___________.
The value of $\lim _{x \rightarrow 0}\left[\frac{\cos 2 x-\cos 4 x}{x^{2}}\right]$ is ___________.
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108
GATE BT 2023 | Question: 27
Match the type of bacteria in Group I with their respective growth properties in Group II. Group I Group II P. Halophile 1. Grows optimally between $20^{\circ} \mathrm{C}$ and $45^{\circ} \mathrm{C}$ Q. Piezophile 2. Grows best at low water activity R. Mesophile 3. Grows at high level of salt S. ... $\text{P-3, Q-1, R-2, S-4}$ $\text{P-4, Q-3, R-1, S-2}$
Match the type of bacteria in Group I with their respective growth properties in Group II.Group IGroup IIP. Halophile1. Grows optimally between $20^{\circ} \mathrm{C}$ an...
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109
GATE BT 2023 | Question: 37
Temperature of a reaction with an activation energy value of $15 \mathrm{kcal} \mathrm{mol}^{-1}$ is increased from $300 \mathrm{~K}$ to $310 \mathrm{~K}$. If the value of the ideal gas constant $(\mathrm{R})$ ... $\left(k_{310} / k_{300}\right)$(rounded off to two decimal places) is _____________.
Temperature of a reaction with an activation energy value of $15 \mathrm{kcal} \mathrm{mol}^{-1}$ is increased from $300 \mathrm{~K}$ to $310 \mathrm{~K}$. If the value o...
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GATE BT 2023 | Question: 5
C-value paradox refers to the lack of correlation between genome size and genetic complexity of an organism the presence of genetic sequences that propagate themselves within a genome the coexistence of multiple alleles at a genetic locus the concept that two or more genes may have the same function
C-value paradox refers tothe lack of correlation between genome size and genetic complexity of an organismthe presence of genetic sequences that propagate themselves with...
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111
GATE BT 2023 | Question: 17
Which one of the following is used for global alignment of two protein sequences? Chou-Fasman method Garnier-Osguthorpe-Robson (GOR) method Needleman-Wunsch algorithm Smith-Waterman algorithm
Which one of the following is used for global alignment of two protein sequences?Chou-Fasman methodGarnier-Osguthorpe-Robson (GOR) methodNeedleman-Wunsch algorithmSmith-W...
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112
GATE BT 2023 | Question: 8
Which one of the following is required for the development of B-cells in the bone marrow? Stromal cells Dendritic cells Kupffer cells NK cells
Which one of the following is required for the development of B-cells in the bone marrow?Stromal cellsDendritic cellsKupffer cellsNK cells
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113
GATE BT 2023 | Question: 15
Match the types of RNA in Group I with their corresponding function in Group II. Group I Group II P. mRNA 1. Serves as adaptors between mRNA and amino acids during protein synthesis Q. rRNA 2. Regulates post-transcriptional gene expression R. miRNA 3. Codes for proteins S. tRNA 4. Forms the core of the ... $\text{P-4, Q-3, R-2, S-1}$ $\text{P-2, Q-1, R-4, S-3}$
Match the types of RNA in Group I with their corresponding function in Group II.Group IGroup IIP. mRNA1. Serves as adaptors between mRNA and amino acids during protein sy...
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114
GATE BT 2023 | Question: 32
Which of the following statement(s) is(are) TRUE about fluoroquinolone drugs? They contain quinolone ring(s) They inhibit RNA polymerase They bind to bacterial topoisomerase They bind to $23 S$ rRNA within the $50 \mathrm{~S}$ ribosome subunit
Which of the following statement(s) is(are) TRUE about fluoroquinolone drugs?They contain quinolone ring(s)They inhibit RNA polymeraseThey bind to bacterial topoisomerase...
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115
GATE BT 2023 | Question: 12
In ELISA, which of the following enzymes are conjugated to antibodies for detection of the analyte? P. Alkaline phosphatase Q. Trypsinase R. Horseradish peroxidase S. Amylase $\mathrm{P}$ and $\mathrm{R}$ $\text{P}$ and $\text{Q}$ $\text{Q}$ and $\text{S}$ $\mathrm{R}$ and $\mathrm{S}$
In ELISA, which of the following enzymes are conjugated to antibodies for detection of the analyte?P. Alkaline phosphataseQ. TrypsinaseR. Horseradish peroxidaseS. Amylase...
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116
GATE BT 2023 | Question: 30
Methylation of $\mathrm{CpG}$ islands near the promoter of a gene can inhibit transcription by preventing RNA polymerase binding facilitating repressor binding facilitating heterochromatin formation inducing euchromatin formation
Methylation of $\mathrm{CpG}$ islands near the promoter of a gene can inhibit transcription bypreventing RNA polymerase bindingfacilitating repressor bindingfacilitating ...
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GATE BT 2023 | Question: 45
DNA sample collected from an unidentified bacterial species $(Y)$ contains $13 \%$ of adenine. The $G+C$ content (in percentage) of $Y$ is ____________.
DNA sample collected from an unidentified bacterial species $(Y)$ contains $13 \%$ of adenine. The $G+C$ content (in percentage) of $Y$ is ____________.
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118
GATE BT 2023 | Question: 33
Which of the following is(are) plant protoplast fusogenic agent(s)? Sodium nitrate Polyvinyl alcohol Polyethylene glycol Bromoxynil
Which of the following is(are) plant protoplast fusogenic agent(s)?Sodium nitratePolyvinyl alcoholPolyethylene glycolBromoxynil
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119
GATE BT 2023 | Question: 23
Two fair six-sided dice are thrown. The probability of getting $12$ as the product of the numbers on the dice (rounded off to two decimal places) is __________.
Two fair six-sided dice are thrown. The probability of getting $12$ as the product of the numbers on the dice (rounded off to two decimal places) is __________.
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120
GATE BT 2023 | Question: 11
Intracellular proteins are targeted for proteolytic degradation in proteasomes upon conjugation with ubiquitin integrin peptidase calreticulin
Intracellular proteins are targeted for proteolytic degradation in proteasomes upon conjugation with ubiquitinintegrinpeptidasecalreticulin
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