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Which of the following conditions promote the development of human autoimmune disorders?

  1. Inability to eliminate self-reactive lymphocytes
  2. Generation of auto-antibodies
  3. Ability to eliminate self-reactive T-cells
  4. Induction of regulatory T-cells in the thymus
  1. P,R
  2. Q,S
  3. P,Q
  4. R,S
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