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Carl Woese used the gene sequence of which one of  the following for phylogenetic taxonomy of prokaryotes?

  1. A ribosomal $RNA$ of large ribosomal subunit
  2. A ribosomal $RNA$ of small ribosomal subunit
  3. A ribosomal protein of large ribosomal subunit
  4. A ribosomal protein of small ribosomal subunit
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