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Which of the following statemets are $CORRECT$ about eukaryotic cell cycle?

  1. $CDKs$ can phosphorylate proteins in the absence of cyclins
  2. $CDKs$ can be inactivated by phosphorylation
  3. Degradation of cyclins is required for cell cycle progression
  4. $CDKs$ are not involved in chromosome condensation
  1. $P$ and $R$ only
  2. $P$ and $S$ only
  3. $P, Q$ and $R$ only
  4. $Q$ and $R$ only
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