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The difference in concentrations of an uncharged solute between two compartments is $1.6$-fold. The energy required for active transport of the solute across the membrane separating the two compartments is _________ $cal\:mol^{-1}$  (rounded off to the nearest integer). $(R =1.987\:cal\:mol^{-1}\:K^{-1},\:T=37 \;^{\circ}C)$
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