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Which of the following factors affect the fidelity of $DNA$ polymerase in polymerase chain reaction?

  1. $Mg^{2+}$ concentration
  2. $pH$
  3. Annealing temperature
  1. $P$ and $Q$ only
  2. $P$ and $R$ only
  3. $Q$ and $R$ only
  4. $P, Q$ and $R$
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