# GATE2015-50

Match the antibiotics in $\text{Group I}$ with their modes of action in $\text{Group II}$.
$\begin{array}{|l|l|l|l|} \hline & \text{Group I} && \text{Group II} \\ \hline P. & \text{Chloramphenicol} & 1. & \text{Inhibits protein synthesis by acting} \\ &&& \text{on 30S ribosomal subunit} \\ \hline Q. & \text{Rifampicin} & 3. & \text{Interferes with DNA replication by} \\ &&& \text{inhibiting DNA gyrase} \\ \hline R. & \text{Tetracycline} & 3. & \text{Inhibits protein synthesis by acting on 50S} \\ &&& \text{ribosomal subunit} \\ \hline S. & \text{Quinolone} & 4. & \text{Interferes with RNA polymerase} \\ &&& \text{activity} \\ \hline && 5. & \text{Inhibits } \beta – \text{lactamase activity} \\ \hline \end{array}$
1. $\text{P-1, Q-2, R-3, S-5}$
2. $\text{P-3, Q-4, R-1, S-2}$
3. $\text{P-3, Q-2, R-1, S-4}$
4. $\text{P-1, Q-4, R-3, S-2}$