0 0 votes Since mammalian cells are sensitive to shear, scale-up of a mammalian cell process must consider, among other parameters, the following $\text{(given N=rotations/time, D=diameter of impeller)}$ $\pi ND$ $\pi N^2D$ $\pi ND^2$ none of these Bioreaction Engineering gate2014 bioreaction-engineering cell-biology engineering-principles-applied-to-biological-systems + – Milicevic3306 7.9k points answer comment Share Follow 0 reply Please log in or register to add a comment.