Recent questions and answers in Bioprocess Engineering and Process Biotechnology

A microbial culture (following Monod model for growth) has a maximum specific growth rate of $0.1 \mathrm{~h}^{-1}$, Monod constant of $1 \mathrm{mg} \mathrm{L}^{-1}$ and...

Match enzymes in $\text{Group I}$ with their corresponding industrial application in $\text{Group II}$.$$\begin{array}{|l|l|l|l|} \hline & \textbf{Group I} && \textbf{Gro...

The specific growth rate of a yeast having a doubling time of $0.693 \; \text{h}$ (rounded off to nearest integer) is ________ $\text{h}^{-1}.$

A microorganism is grown in a batch culture using glucose as a carbon source. The apparent growth yield is $0.5 \frac{\text{g biomass}}{\text{g substrate}}.$ The initial ...

The overall stoichiometry for an aerobic cell growth is$3 \text{C}_{6} \text{H}_{12} \text{O}_{6} + 2.5 \text{NH}_{3} + \text{O}_{2} \rightarrow 1.5 \text{C}_{a} \text{H}...

E. coli is cultivated in a chemostat operated at a dilution rate of $0.2 h^{-1}$. The values of biomass yield due to oxygen consumption and the steady state biomass conce...

A fed batch process is running at quasi-steady state with respect to substrate and biomass concentration. At $2 \mathrm{~h}$, the culture volume is $500 \mathrm{~L}$ with...

Fed batch cultivation is suitable for which of the following?Processes with substrate inhibitionProcesses with product inhibitionHigh cell density cultivationP and Q only...

It is desired to scale-up a fermentation from $1L$ to $1000L$ vessel by maintaining a constant power-to-volume ratio. The small fermenter is operated at an agitator speed...

Which one of the following represents non-growth associated product formation kinetics in a bioprocess system? $X$ and $P$ denote viable cell and product concentrations, ...

​​​​Correctly match the following Product classes with their representative Products.Product classProductP. Biofuel1. CellulaseQ. Bioplastic2. CephalosporinR. Industrial ...

​​​​Which of the following fluids exhibit(s) non-Newtonian behaviour at $25^{\circ} \mathrm{C}$ ?ToothpasteMercuryBrineBlood plasma

A binary mixture of benzene and toluene under vapour-liquid equilibrium at $80^{\circ} \mathrm{C}$ follows ideal Raoult's law. At this condition, the saturation pressures...

An industrial fermentor containing $10,000\:L$ of medium needs to be sterilized. The initial spore concentration in the medium is $10^{6}$ spores $mL^{-1}$. The desired ...

Which one of the following statements is correct about Reynolds Number $\left(N_{R e}\right)$ in a stirred tank bioreactor?$N_{R e}$ is independent of the viscosity of th...

Fermentation medium is cooled from $121^{\circ} \mathrm{C}$ to $30{ }^{\circ} \mathrm{C}$ in a double pipe heat exchanger. If cold water is flowing in the counter-current...

For a double-pipe heat exchanger, the inside and outside heat transfer coefficients are $100$ and $200 \; \text{W m}^{-2} \text{K}^{-1},$ respectively. The thickness and ...

A $2 \: \mathrm{L}$ bioreactor is being operated as a chemostat, at a flow rate of $0.8 \: \mathrm{~L} / \mathrm{h}$ and sterile feed of $10 \: \mathrm{~g} / \mathrm{L}$ ...

A hot, freshly-sterilised fermentation medium is cooled in a double-pipe heat-exchanger. The medium enters the inner pipe of the exchanger at $95^{\circ} \mathrm{C}$ and ...

​​​​An enzyme immobilised in a porous spherical pellet, catalyses a strongly mass-transfer limited first-order reaction. The effectiveness factor for the immobilised enzy...

​​​​For a specific bioreactor configuration, the power requirement for a Rushton-turbine impeller agitating an unaerated Newtonian fluid in the turbulent regime will bepr...

The following reaction represents biomass synthesis from hexadecane$\mathrm{C}_{16} \mathrm{H}_{34}+12.5 \mathrm{O}_2+2.13 \mathrm{NH}_3 \rightarrow 10.6 \mathrm{CH}_{1.6...