Recent questions tagged cell-biology

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Cancer cells display a high level of heterogeneity in the expression of TP$53$ protein. Which of the following techniques can be directly used to determine the intratumor...
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Which of the following enzyme is involved in the protection of cells from reactive oxygen species?HexokinaseGlucose $6$-phosphate dehydrogenaseEnolasePyruvate kinase
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For monoclonal antibody production, hypoxanthine $\_\_\_\_$.allows DNA synthesis in the absence of de novo dTMP synthesisallows purine synthesis in cells containing HGPRT...
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Which one of the following options represents the products of light reactions of photosynthesis in plants?$\mathrm{O}_{2} / \mathrm{NADH} / \mathrm{H}_{2}$$\mathrm{O}_{2}...
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Which of the following is/are extra-cellular matrix protein(s)?MyosinFibronectinLaminCollagen
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To determine the viable cell count of a bacterial culture, you have plated $50 ~\mu \mathrm{~L}$ of a $100$ -fold diluted sample of the culture on a nutrient agar plate a...
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Match the biomolecules in Column $\text{I}$ with their function given in Column $\text{II}$\[\begin{array}{|l|l|}\hline\text{Column I} & \text{Column II} \\\hline\text{P....
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In the process of generating a clonal mammalian cell line, a single cell was seeded in a well of a cell culture plate. After the first $48$ hours, one of the progeny cell...
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​​​​​Which one of the following hosts is used in mammalian cell culture for the production of glycosylated recombinant therapeutic proteins?Pichia pastorisSf$9$ cellsEsch...
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​​​​Which of the following features is/are used to distinguish Archaea from Bacteria?Gram-stainingPeptidoglycan in the cell wallPresence of N -acetylglucosamine$16 S$ rRN...
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​​​​Which of the following proteins is/are involved in intraflagellar transport?MicrotubulesMyosinActinKinesin
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​​​​Which of the following statements is/are true about telomerase?Telomerase has $5^{\prime}-3^{\prime}$ DNA-dependent DNA polymerisation activityTelomerase has $5^{\pri...
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Co-translational translocation of proteins is observed in $\_\_\_\_\_\_\_$.endoplasmic reticulumGolgi complexmitochondriaperoxisomes
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During normal embryonic development of the mice paw, elimination of cells from the inter-digital space is due to $\_\_\_\_\_\_\_$.apoptosismeiosismutagenesisnecrosis
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A cultured skin fibroblast cell of a goat ' $\mathrm{P}$ ' was fused with an enucleated ovum of a goat ' $\mathrm{Q}$ '. The resultant activated early embryo was then tra...
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Which one of the following is an insect cell line?$\text{HEK} 293$$\text{Sf}9$$\text{DH}5$ $\alpha$ $\text{CHO}$
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Krebs $\text{(TCA)}$ cycle is $\_\_\_\_\_\_$ pathway.only an anaboliconly a catabolic an amphibolica pyogenic
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Match the item (Column I) with its corresponding use (Column II).\begin{array}{|c|c|c|}\hline \text{Column I} & \text{Column II} \\\hline \text{P. Glutamine} & 1. \text{D...
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Match the item in Column I with the corresponding technique in Column II.\begin{array}{|c|c|c|}\hline & \text{Column I} & \text{Column II} \\\hline & \text{P. Blue laser}...
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Which of the following is/are considered as biotic elicitor(s) in plant cell culture?CellulaseChitinChitosanMercuric chloride
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Under which of the following conditions, a mammalian somatic cell fails to undergo mitosis during cell cycle?Initiation of cell plate formationIncomplete DNA replicationC...
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E. coli is inoculated in a shake flask containing nutrient rich medium. The initial number of viable cells in the medium is $10^2$. After few hours, the number of viable ...
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Acetylcholine released by the parasympathetic nerves has which one of the following functions in the heart pacemaker cells?It binds to $\text{GPCR}$ and activates $\text{...
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Which one of the following is required for the development of B-cells in the bone marrow?Stromal cellsDendritic cellsKupffer cellsNK cells
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Intracellular proteins are targeted for proteolytic degradation in proteasomes upon conjugation with ubiquitinintegrinpeptidasecalreticulin
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In hybridoma technology, which one of the following enzymes is absent in the myeloma cells that are used for monoclonal antibody production?Hypoxanthine-guanine phosphori...
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Match the types of RNA in Group I with their corresponding function in Group II.Group IGroup IIP. mRNA1. Serves as adaptors between mRNA and amino acids during protein sy...
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Which of the following statement(s) is(are) TRUE about induced pluripotent stem cells?They can self-renewThey require specific signals to maintain their stemnessThey cann...
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Which of the following is(are) plant protoplast fusogenic agent(s)?Sodium nitratePolyvinyl alcoholPolyethylene glycolBromoxynil
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Match the component of eukaryotic cells (Column I) with its respective function (Column II).$$\begin{array}{lll} \textbf{Column I} & & \textbf{Column II} \\ \text{P. Lyso...
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In animal cells, the endogenously produced $\text{miRNAs}$ silence gene expression bybase pairing with the $3’$-untranslated region of specific $\text{mRNAs}$blocking $\t...
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Match the media component used in mammalian cell culture (Column I) with its respective role (Column II).$$\begin{array} {lll} \textbf{Column I} & & \textbf{Column II} \\...
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Match the cell type (Column I) with its function (Column II).$$\begin{array} {lll} \textbf{Column I} & & \textbf{Column II} \\ \text{P. B cells} & & \text{1. Humoral immu...
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The enzymes involved in ubiquitinylation of cell-cycle proteins are$\text{E}_{1}$ and $\text{E}_{2}$ Only$\text{E}_{1}$ and $\text{E}_{3}$ Only$\text{E}_{1}$ and $\text{E...
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Which of the following is(are) $\text{COMMON}$ feature(s) for both aerobic and anaerobic bacterial cultures?Glycolysis$\text{NAD}^{+}$ is the oxidising agentOxidative pho...
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Which of the following statement(s) regarding trafficking in eukaryotic cells is(are) CORRECT?Dynamic binds $\text{GTP}$ and is involved in vesicle buddingDynamic is invo...
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Figure below depicts simplified metabolic and transport reactions taking place in the production of $\text{B}$ from $\text{A}$ in a cell. The subscript $ i\text{’}$ refer...
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The enzyme that transcribes the eukaryotic genes encoding precursor ribosomal $\text{RNAs}\; (\text{pre-RNAs}$) of $28S$, $18S$ and $5.8S$ $\text{rRNA}$s is$\text{RNA}$ p...
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The process by which intracellular macromolecules are supplied for lysosomal degradation during nutrient starvation isapoptosisautophagyphagocytosispinocytosis
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Which of the following cell organelle(s) is/are surrounded by a single phospholipid membrane?Golgi apparatusLysosomeMitochondriaNucleus