Recent questions tagged genetics-and-evolutionary-biology

Which component of the $\text{CRISPR/Cas9}$ gene editing system is $\text{NOT}$ of natural origin?$\text{CAS9}$ protein$\text{CRISPR}$ repeats$\text{PAM}$ sequence$\text{...

Match the genetic disorders in Column $\text{I}$ to the corresponding underlying cause in Column $\text{II}$\[\begin{array}{|l|l|}\hline\text{Column I} & \text{Column II}...

Messenger $\text{RNAs (mRNAs)}$ translate to generate polypeptides and the translation terminates at the $\text{UGA, UAG}$ or $\text{UAA}$ stop codons. The $\text{AGA}$ c...

The RNA sequence below depicts the part of a $330$ nucleotides long $\text{mRNA}$ and it encodes the $\text{C}$-terminal portion of a protein.$5^{\prime}-\ldots \ldots$ $...

A disease-associated allele shows $\text{X}$-linked recessive inheritance. If the mother is a carrier of the disease, the father is genetically normal and the child born ...

​​​​Which one of the following is true for piRNAs?piRNAs silence transposable elements in germ cellspiRNA is the abbreviation of $P$-element interacting RNApiRNAs modify ...

​​​​Correctly match the herbicide with its mode of development of resistance in plants.\begin{array}{|l|l|}\hline \textbf{Herbicide } & \textbf{Mode of development of res...

​​​The blood group of the mother is $\mathrm{A}^{+}$and that of the father is $\mathrm{AB}^{+}$. Which of the following statements is/are correct?Probability of the offsp...

Mendel's 'law of segregation' applies to the segregation of $\_\_\_\_\_\_\_\_$ during gamete formation.mitochondrial genesalleles of a genelinked genes on the same chromo...

A cultured skin fibroblast cell of a goat ' $\mathrm{P}$ ' was fused with an enucleated ovum of a goat ' $\mathrm{Q}$ '. The resultant activated early embryo was then tra...

Match the genetic disorder (Column I) with its molecular basis (Column II).\begin{array}{|c|c|c|}\hline \text{Column I} & \text{Column II} \\\hline \text{P. Sickle-cell a...

The evolution of wings in bats and insects is an example of $\_\_\_\_\_\_\_$ evolution.convergentdivergentneutralparallel

Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $[\mathrm{r}]$.Assertion $[\mathrm{a}]$: In multicellular organisms, cells o...

Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $\text{[r]}$.Assertion $\text{[a]}$: Chromosome mutations can change the str...

C-value paradox refers tothe lack of correlation between genome size and genetic complexity of an organismthe presence of genetic sequences that propagate themselves with...

The event(s) that lead(s) to inactivation of tumor suppressor genes in cancer cells is(are)gene amplificationpromoter methylationloss of heterozygosityhistone acetylation

Methylation of $\mathrm{CpG}$ islands near the promoter of a gene can inhibit transcription bypreventing RNA polymerase bindingfacilitating repressor bindingfacilitating ...

Assuming independent assortment and no recombination, the number of different combinations of maternal and paternal chromosomes in gametes of an organism with a diploid n...

Which of the following conditions will contribute to the stability of a gene pool in a natural population?Large populationNo net mutationNon-random matingNo selection $...

Which of the following statement(s) is(are) CORRECT regarding the $lac$ operon in $E. coli$ when grown in the presence of glucose and lactose?At low glucose level, the op...

A circular plasmid has three different but unique restriction sites for enzymes $‘\text{a'}, ‘\text{b'}$ and $‘\text{c'}.$ When enzymes $‘\text{a'}$ and $‘\text{b'}$ are ...

Number of unrooted trees in a phylogeny of five sequences is$3$$15$$105$$945$

The order of genes present in a chromosome is as followsWhich one of the following rearrangements represents a paracentric inversion?

In $\textit{Neurospora crassa}$, a mutation in the $\textit{poky}$ gene results in a slow growth phenotype (poky). The results of four crosses are given below.wild-type $...

In a Mendel’s dilhybrid experiment, a homozygous pea plant with round yellow seeds was crossed with a homozygous plant with wrinkled green seeds.$F_1$ intercross produced...

In a random mating population, $Y$ and $y$ are dominant and recessive alleles, respectively. If the frequency of $Y$ allele in both sperm and egg is $0.70$, then the freq...

Which one of the following is coded by the $ABO$ blood group locus in the human genome?Acyl transferaseGalactosyltransferaseTransposase$\beta$-Galactosidase

Determine the correctness or otherwise of the following Assertion $[a]$ and the Reason $[r]$Assertion $[a]$ : It is possible to regenerate a whole plant from a single pla...

In pea plants, purple color of flowers is determined by the dominant allele while white color is determined by the recessive allele. A genetic cross between two purple fl...

The molecular mass of a protein is $22\:kDa$. The size of the $\text{cDNA}$ (excluding the untranslated regions) that codes for this protein is __________ $kb$ (rounded o...

$W,X$ and $Y$ are the intermediates in a biochemical pathway as shown below:$$S \cdots \cdots \rightarrow W\rightarrow X\rightarrow Y\rightarrow Z$$Mutants auxotrophic fo...

In tomato plant, red ($R$) is dominant over yellow ($r$) for fruit color and purple ($P$) is dominant over green ($p$) for stem color. Fruit color and stem color assort i...

Determine the correctness or otherwise of the following Assertion [$a$] and the Reason [$r$].Assertion [$a$]: Embryonic stem cells are suitable for developing knockout mi...

Which of the following statements about gene therapy are CORRECT?Affected individuals, but not their progeny, can be cured through germline gene therapyAffected individua...

Determine the correctness or otherwise of the following Assertion [$a$] and the Reason [$r$].Assertion [$a$]: A genetically engineered rice that produces beta-carotene in...

$E$ coli was grown in $^{15}N$ medium for several generations. Cells were then transferred to $^{14}N$ medium, allowed to grow for $4$ generations and $DNA$ was isolated ...

The amino acid sequence of a peptide is $Phe-Leu-lle-Met-Ser-Leu$. The number of codons that encode the amino acids present in this peptide is given below:Phe: $2$ codons...

Which of the following processes can increase genetic diversity of bacteria in nature?ConjugationTransformationTransductionTransfection$P$ only$P$ and $Q$ only$P, Q$ and ...

Which one of the following is NOT a therapeutic agent based on nucleic acid for the treatment of genetic disorders?Antisense oligonucleotideRibozymeAptamerAvidin