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Which of the following statements about gene therapy are CORRECT?

  1. Affected individuals, but not their progeny, can be cured through germline gene therapy
  2. Affected individuals, as well as their progeny, can be cured through germline gene therapy
  3. Affected individuals, but not their progeny, can be cured through somatic gene therapy
  4. Affected individuals, as well as their progeny, can be cured through somatic gene therapy
  1. $P$ and $R$ only
  2. $P$ and $S$ only
  3. $Q$ and $R$ only
  4. $Q$ and $S$ only
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