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A microbial strain is cultured in a 100 I. stirred fermenter for secondary metaboliteproduction. If the specic rate of oxygen uptake is 0.4 h'1 and the oxygen solubility in thebroth is 8 mg L. then the volumetric mass transfer coefficient (Km) (in sl) of oxygenrequired to achieve a maximum cell concentration of 12 gL is (up to two decimalplaces)

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