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Q. 13 Gram-positive bacteria are generally resistant to complement-mediated lysis because

  1. thick peptidoglycan layer prevents insertion of membrane attack complex into the irmer membrane
  2. Gram-positive bacteria import the membrane attack complex and inactivate it
  3. membrane attack complex is degraded by the proteases produced by the Gram-positive bacteria
  4. Gram-positive bacteria cannot activate the complement pathway
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