Questions without answers in Bioinformatics

BLAST and its extensions can be used to determine similarity of a query protein sequence with which of the following database(s)?A database of translated nucleotide seque...

​​​​Correctly match the following Bioinformatic tool/Database with its respective Utility.\begin{array}{|l|l|}\hline \textbf{Bioinformatic tool/Database} & \textbf{Utilit...

Which one of the following programs is used for finding distantly related (or remote) protein homologs?BLASTNBLASTXPSI-BLASTTBLASTX

Which one of the following is used for global alignment of two protein sequences?Chou-Fasman methodGarnier-Osguthorpe-Robson (GOR) methodNeedleman-Wunsch algorithmSmith-W...

Which of the following is $\text{NOT}$ used for generating an optimal alignment of two nucleotide sequences?Gap penaltiesMatch scoresMismatch scoresNucleotide composition

The maximum parsimony method is used to construct a phylogenetic tree for a set of sequences. Which one of the following statements about the method is $\text{CORRECT}?$I...

Number of unrooted trees in a phylogeny of five sequences is$3$$15$$105$$945$

Which one of the following methods is used to test the significance of a predicted phylogeny?BootstrapMaximum likelihoodMaximum parsimonyMinimum evolution

Which one of the following tools is used to compare all the possible six-open reading frames of a given nucleotide query sequence with all the available six-open reading ...

Which of the following statements are $CORRECT$ when a protein sequence database is searched using the $BLAST$ algorithm?A larger E-value indicates higher sequence simila...

The sequence of a $1$ $Mb$ long $DNA$ is random. This $DNA$ has all four bases occurring in equal proportion. The number of nucleotides, on average, between two successiv...

Which one of the following is a database of protein sequence motifs?$PROSITE$$TrEMBL$$SWISSPROT$$PDB$

The number of possible rooted trees in a phylogeny of three species is ______.

Which one of the following is NOT an algorithm for building phylogenetic trees?Maximum parsimonyNeighbor joiningMaximum likelihoodBootstrap

Identify the file format given below:$>$P$1$; JMFDProtein X – Homo sapiensMKALTARQQEVFDLIRDHISRTLRQQGDWLGDEFASTANBRFGCG

How many rooted and unrooted phylogenetic trees, respectively, are possible with four different sequences?$3$ and $15$$15$ and $3$$15$ and $12$$12$ and $3$

Consider the following multiple sequence alignment of four DNA sequences.$$\begin{array}{cccc} A & C & T & A \\ A & C & T & G \\ A & G & T & C \\ A & G & C & T \end{arra...

The algorithm for BLAST is based onDynamic ProgrammingHidden Markov Modelk-tuple analysisNeural Network

In an affine gap penalty model, if the gap opening penalty $-20$, gap extension penalty is $-4$ and gap length is $8$, the gap score is__________.

Determine the correctness or otherwise of the following $\text{Assertion (a) and Reason (r)}$.$\text{Assertion:}$ $\text{UPGMA}$ method produces ultrametric tree.$\text{R...

Calculate the percentage sequence identity for the pairwise alignment given below. ______________$\text{HELLO-}$$\text{YELLOW}$

While searching a database for similar sequences, E value does NOT depend on thesequence lengthnumber of sequences in the databasescoring systemprobability from a normal ...

An example of a derived protein structure database isPfamSCOPGEOProsite

An example of a program for constructing a phylogenetic tree isphylipphrapprodomPHDsec