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Which one of the following tools is used to compare all the possible six-open reading frames of a given nucleotide query sequence with all the available six-open reading frames of the nucleotide sequence database?

  1. $\text{BLASTN}$
  2. $\text{BLASTX}$
  3. $\text{TBLASTN}$
  4. $\text{TBLASTX}$
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