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Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $[\mathrm{r}]$.Assertion $[\mathrm{a}]$: In multicellular organisms, cells o...
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Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $\text{[r]}$.Assertion $\text{[a]}$: Chromosome mutations can change the str...
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C-value paradox refers tothe lack of correlation between genome size and genetic complexity of an organismthe presence of genetic sequences that propagate themselves with...
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Dendritic cells are involved in cross-presentation of antigens. Which of the following protein(s) is(are) required for cross-presentation?P. Basic leucine zipper ATF-like...
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Which one of the following is required for the development of B-cells in the bone marrow?Stromal cellsDendritic cellsKupffer cellsNK cells
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Which one of the following statements is TRUE about leghemoglobin?It binds oxygen to protect nitrogenaseIt binds hemoglobin to protect oxygenaseIt binds oxygen to protect...
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Intracellular proteins are targeted for proteolytic degradation in proteasomes upon conjugation with ubiquitinintegrinpeptidasecalreticulin
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In ELISA, which of the following enzymes are conjugated to antibodies for detection of the analyte?P. Alkaline phosphataseQ. TrypsinaseR. Horseradish peroxidaseS. Amylase...
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In hybridoma technology, which one of the following enzymes is absent in the myeloma cells that are used for monoclonal antibody production?Hypoxanthine-guanine phosphori...
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Which of the following methods are used for detection of DNA and RNA, respectively?Southern and Northern blotting Southern and Western blottingNorthern and Southern blott...
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Match the types of RNA in Group I with their corresponding function in Group II.Group IGroup IIP. mRNA1. Serves as adaptors between mRNA and amino acids during protein sy...
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Which one of the following programs is used for finding distantly related (or remote) protein homologs?BLASTNBLASTXPSI-BLASTTBLASTX
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Which one of the following is used for global alignment of two protein sequences?Chou-Fasman methodGarnier-Osguthorpe-Robson (GOR) methodNeedleman-Wunsch algorithmSmith-W...
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Fabry disease in humans is a X-linked disease. The probability (in percentage) for a phenotypically normal father and a carrier mother to have a son with Fabry disease is...
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The value of $\lim _{x \rightarrow 0}\left[\frac{\cos 2 x-\cos 4 x}{x^{2}}\right]$ is ___________.
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Two fair six-sided dice are thrown. The probability of getting $12$ as the product of the numbers on the dice (rounded off to two decimal places) is __________.
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If $7^{3 x}=216$, the value of $7^{-x}$ (rounded off to three decimal places) is _____________.
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The distance between the two points of intersection of $x^{2}+y=7$ and $x+y=7$ (rounded off to two decimal places) is ___________.
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Match the immune tolerance mechanisms in Group I with their respective outcomes in Group II.Group IGroup IIP. Anergy1. Elimination of activated T-cells after antigen clea...
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Match the type of bacteria in Group I with their respective growth properties in Group II.Group IGroup IIP. Halophile1. Grows optimally between $20^{\circ} \mathrm{C}$ an...
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Match the virus in Group I with the type of genome it contains in Group II.Group IGroup IIP. T4 bacteriophage1. dsRNAQ. SARS-CoV-22. ssDNAR. Pseudomonas phage $\phi 6$3. ...
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The event(s) that lead(s) to inactivation of tumor suppressor genes in cancer cells is(are)gene amplificationpromoter methylationloss of heterozygosityhistone acetylation
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Methylation of $\mathrm{CpG}$ islands near the promoter of a gene can inhibit transcription bypreventing RNA polymerase bindingfacilitating repressor bindingfacilitating ...
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Which of the following statement(s) is(are) TRUE about induced pluripotent stem cells?They can self-renewThey require specific signals to maintain their stemnessThey cann...
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Which of the following statement(s) is(are) TRUE about fluoroquinolone drugs?They contain quinolone ring(s)They inhibit RNA polymeraseThey bind to bacterial topoisomerase...
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Which of the following is(are) plant protoplast fusogenic agent(s)?Sodium nitratePolyvinyl alcoholPolyethylene glycolBromoxynil
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Direct DNA transfer method(s) used for plant genetic engineering is(are)microparticle bombardmentelectroporationpolyethylene glycol treatmentAgrobacterium-mediated transf...
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Which of the following vector(s) is(are) used to clone a DNA fragment of size $220 \mathrm{~kb}$?Bacterial artificial chromosomeYeast artificial chromosomeCosmids$\text{p...
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Temperature of a reaction with an activation energy value of $15 \mathrm{kcal} \mathrm{mol}^{-1}$ is increased from $300 \mathrm{~K}$ to $310 \mathrm{~K}$. If the value o...
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Aqueous two-phase extraction is used to recover } \alpha \text {-amylase from a solution. A polypropylene glycol-dextran mixture is added and the solution separates into ...
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E. coli cultivated at $298 \mathrm{~K}$ uptakes an uncharged compound (A) by passive diffusion. The intracellular and extracellular concentrations of $\mathrm{A}$ are $0...
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If there are three unrooted trees for four protein sequences, the number of rooted trees for the same number of sequences is _______________.
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The number of different possible ways of forming five intramolecular disulfide bonds with ten cysteine residues of a protein is ______________.
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The following schematic diagram shows a chemostat with cell recyclewhere $\mathrm{F}_0$ and $\mathrm{F}_{\mathrm{r}}$ are the volumetric flow rates (in $L \cdot h^{-1}$ )...
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An enzyme (E) catalyzes the biochemical reaction $A \rightarrow B$ with $k_{c a t}$ equal to $500 s^{-1}$. If the initial reaction velocity $\left(V_{0}\right)$ is $10 \m...
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DNA sample collected from an unidentified bacterial species $(Y)$ contains $13 \%$ of adenine. The $G+C$ content (in percentage) of $Y$ is ____________.
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If $1000 \mathrm{bp}$ of a double-helical DNA weighs $1 \times 10^{-18} \mathrm{gm}$ and distance between two $\mathrm{bp}$ is $0.34 \mathrm{~nm}$, the total amount of DN...
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A protein has three identical sites arranged at the vertices of an equilateral triangle. If one site is filled with a dye (donor), the measured quantum yield $\left(\phi_...
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If $A=\left(\begin{array}{ll}1 & 2 \\ 3 & 5\end{array}\right)$, the value of $\left|A^{4}+3 A^{2}-5 A+6 I\right|$ is _____________.
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If $f(x)=\frac{\sin x+\cos x}{\sin x-\cos x}$, the value of $f^{\prime}(x)$ at $x=0$ is ___________.