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 The amino acid substitution matrices in decreasing order of stringency for comparing protein sequences are

  1. PAM$250$, PAM$120$, PAM$100$
  2. PAM$100$, PAM$120$, PAN$250$
  3. PAM$250$, PAM$100$, PAM$120$
  4. PAM$120$, PAM$250$, PAM$100$
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