A DNA sequence, $\textrm{5’ -ATGGACGTGCTTCCCAAAGCATCGGGC- 3’}$, is mutated to obtain
- $\textrm{5'-ATGGACGTGCTTC}\textbf{a}\textrm{CAAAGCATCGGGC- 3'}$
- $\textrm{5'-ATGGACGTGCTTCCC}\textbf{g}\text{AAAGCATCGGGC-3'}$
- $\textrm{5'-ATGGACGTGCTTCC- AAAGCATCGGGC- 3'}$
- $\textrm{5'-ATGGACGTGCTTCCCAA}\textbf{t}\textrm{GCATCGGGC- 3'}$
- $\textrm{5'-ATGGACG}\textbf{a}\textrm{GCTTCCCAAAGCATCGGGC- 3'}$
[Point mutations are showm in the lower case or $’-’$ Within the sequences]
Which of the above mutant sequences DO NOT have frame-shift?
- P, Q and S
- P, S and T
- Q, R and S
- Q, S and T