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Which of the following statements about reversible enzyme inhibitors are $\text{CORRECT}?$

  1. Uncompetitive inhibitors bind only to the enzyme-substrate complex
  2. Non-competitive inhibitors bind only at a different site from the substrate
  3. Competitive inhibitors bind to the same site as the substrate


  1. $\text{P}$ and $\text{Q}$ only
  2. $\text{P}$ and $\text{R}$ only
  3. $\text{Q}$ and $\text{R}$ only
  4. $\text{P, Q}$ and $\text{R}$
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