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GATE BT 2025 | Question: 40

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​​​​Which of the following statements about initiation of DNA replication in eukaryotes is/are true?

  1. DNA replication is initiated at the origin of replication licensed by loading of Mcm helicase complex
  2. Loading of Mcm helicase complex takes place in S phase
  3. Mcm helicase complex are activated by S-Cdks
  4. Mcm helicase complex is responsible for loading of origin recognition complex

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