Recent questions tagged immunology

Match the cells in $\text{Group I}$ with their corresponding entries in $\text{Group II}$$\begin{array}{|l|l|l|l|} \hline & \textbf{Group I} && \textbf{Group II} \\ \hlin...

Three distinct antigens $X, Y$ and $Z$ were used to raise antibodies. Antigen $Z$ was injected in a mouse on day zero followed by the administration of antigens $X$ and $...

Gram-positive bacteria are generally resistant to complement-mediated lysis becausethick peptidoglycan layer prevents insertion of membrane attack complex into the irmer ...

Reactions between antibodies and antigens that are detected by precipitate formation in an agar gel are referred asimmunoprecipitation assayimmunodiffusion assayimmunoagg...

In a mouse genome, the numbers of functional $V\alpha, J\alpha, V\beta, D\beta, J\beta$ gene segments are $\text{79, 38, 21, 2 and 11,}$ respectively. The total number of...

Match the immunoglobulin class in $\text{Group I}$ with its properties in $\text{Group II}$$\begin{array}{|l|l|l|l|} \hline & \textbf{Group I} && \textbf{Group II} \\ \hl...

Endogenous antigens are presented on to the cell surface along with$MHC-II$$MHC-I$$F_c\gamma$receptorcomplement receptor

The role of an adjuvant istoprolong the persistence of antigencross link the antigenincrease the size of antigenavoid inflammation

The first humanized monoclonal antibody approved for the treatment of breast cancerisRituximabCetuximabBevacizumabHerceptin

Protein A, which has strong affinity to $F_C$ region of immunoglobulin, is extracted from$\text{Saccharomyces cerevisiae}$$\text{Staphylococcus aureus}$$\text{Streptococc...

Heat inactivation of serum is done to inactivateprionsmycoplasmacomplementpathogenic bacteria

Nude mice refers tomice without skinmice without thymusknockout micetransgenic mice

A humanized antibody is one in which theheavy and light chains are from humanheavy chain is from human and light chain is from mouselight chain is from human and heavy ch...

B-lymphocytes originate from the bone marrow whereas T-lymphocytes originate fromthymusbone marrowspleenliver

Identification of blood groups involvesprecipitationneutralizationopsonizationagglutination

Idiotypic determinants of an antibody are associated with theconstant region of the heavy chainsconstant region of the light chainsvariable regionconstant regions of ligh...

Which one of the following statements is true with regard to processing and presentation of protein antigens?In the class II MHC pathway, protein antigens in the cytosol ...

Which one of the combinations of the following statements is true about antibody structure?Limited proteolysis of rabbit IgG with the enzyme pepsin generates two antigen-...

Which one of the following amino acids is catalyzed by activated macrophages to produce reactive nitrogen species?ArginineAsparagineCysteineHistidine

Which of the following cytokines are endogenous pylogens?Tumor necrosis factor-$\alpha$Interleukin-$1$Transforming growth factor-$\beta$Interleukin-$10$P and Q onlyP and ...

Which one of the following is NOT a principal component of innate immunity?Mucosal epitheliaDendritic cellsComplement systemMemory B-cells