Recent questions in General Biology

C-value paradox refers tothe lack of correlation between genome size and genetic complexity of an organismthe presence of genetic sequences that propagate themselves with...

Dendritic cells are involved in cross-presentation of antigens. Which of the following protein(s) is(are) required for cross-presentation?P. Basic leucine zipper ATF-like...

Which one of the following is required for the development of B-cells in the bone marrow?Stromal cellsDendritic cellsKupffer cellsNK cells

Intracellular proteins are targeted for proteolytic degradation in proteasomes upon conjugation with ubiquitinintegrinpeptidasecalreticulin

In ELISA, which of the following enzymes are conjugated to antibodies for detection of the analyte?P. Alkaline phosphataseQ. TrypsinaseR. Horseradish peroxidaseS. Amylase...

Match the types of RNA in Group I with their corresponding function in Group II.Group IGroup IIP. mRNA1. Serves as adaptors between mRNA and amino acids during protein sy...

Which one of the following programs is used for finding distantly related (or remote) protein homologs?BLASTNBLASTXPSI-BLASTTBLASTX

Which one of the following is used for global alignment of two protein sequences?Chou-Fasman methodGarnier-Osguthorpe-Robson (GOR) methodNeedleman-Wunsch algorithmSmith-W...

The distance between the two points of intersection of $x^{2}+y=7$ and $x+y=7$ (rounded off to two decimal places) is ___________.

Match the immune tolerance mechanisms in Group I with their respective outcomes in Group II.Group IGroup IIP. Anergy1. Elimination of activated T-cells after antigen clea...

Match the type of bacteria in Group I with their respective growth properties in Group II.Group IGroup IIP. Halophile1. Grows optimally between $20^{\circ} \mathrm{C}$ an...

Match the virus in Group I with the type of genome it contains in Group II.Group IGroup IIP. T4 bacteriophage1. dsRNAQ. SARS-CoV-22. ssDNAR. Pseudomonas phage $\phi 6$3. ...

The event(s) that lead(s) to inactivation of tumor suppressor genes in cancer cells is(are)gene amplificationpromoter methylationloss of heterozygosityhistone acetylation

Methylation of $\mathrm{CpG}$ islands near the promoter of a gene can inhibit transcription bypreventing RNA polymerase bindingfacilitating repressor bindingfacilitating ...

Which of the following statement(s) is(are) TRUE about induced pluripotent stem cells?They can self-renewThey require specific signals to maintain their stemnessThey cann...

Which of the following statement(s) is(are) TRUE about fluoroquinolone drugs?They contain quinolone ring(s)They inhibit RNA polymeraseThey bind to bacterial topoisomerase...

Temperature of a reaction with an activation energy value of $15 \mathrm{kcal} \mathrm{mol}^{-1}$ is increased from $300 \mathrm{~K}$ to $310 \mathrm{~K}$. If the value o...

E. coli cultivated at $298 \mathrm{~K}$ uptakes an uncharged compound (A) by passive diffusion. The intracellular and extracellular concentrations of $\mathrm{A}$ are $0...

An enzyme (E) catalyzes the biochemical reaction $A \rightarrow B$ with $k_{c a t}$ equal to $500 s^{-1}$. If the initial reaction velocity $\left(V_{0}\right)$ is $10 \m...

DNA sample collected from an unidentified bacterial species $(Y)$ contains $13 \%$ of adenine. The $G+C$ content (in percentage) of $Y$ is ____________.

If $1000 \mathrm{bp}$ of a double-helical DNA weighs $1 \times 10^{-18} \mathrm{gm}$ and distance between two $\mathrm{bp}$ is $0.34 \mathrm{~nm}$, the total amount of DN...

A protein has three identical sites arranged at the vertices of an equilateral triangle. If one site is filled with a dye (donor), the measured quantum yield $\left(\phi_...

A dNTP master-mix is prepared by combining $40 \mu L$ of each $20 \mathrm{mM}$ dNTP stock (dATP, dCTP, dGTP and dTTP). $4 \mu L$ of this dNTP master-mix is added to a PCR...

In binomial nomenclature, the name of a bacterial strain is written with the first letter of __________ word(s) being capitalized.firstsecondneitherfirst and second

The type of nucleic acid present in $\lambda$-phage isDouble stranded $\text{DNA}$Single stranded circular $\text{DNA}$Single stranded $\text{DNA}$Single stranded $\text{...

Which of the following statements about reversible enzyme inhibitors are $\text{CORRECT}?$Uncompetitive inhibitors bind only to the enzyme-substrate complexNon-competitiv...

Match the component of eukaryotic cells (Column I) with its respective function (Column II).$$\begin{array}{lll} \textbf{Column I} & & \textbf{Column II} \\ \text{P. Lyso...

In animal cells, the endogenously produced $\text{miRNAs}$ silence gene expression bybase pairing with the $3’$-untranslated region of specific $\text{mRNAs}$blocking $\t...

Which of the following is $\text{NOT}$ used for generating an optimal alignment of two nucleotide sequences?Gap penaltiesMatch scoresMismatch scoresNucleotide composition

Match the media component used in mammalian cell culture (Column I) with its respective role (Column II).$$\begin{array} {lll} \textbf{Column I} & & \textbf{Column II} \\...

Match the cell type (Column I) with its function (Column II).$$\begin{array} {lll} \textbf{Column I} & & \textbf{Column II} \\ \text{P. B cells} & & \text{1. Humoral immu...

Match the stationary phase (Column I) with its corresponding chromatography technique (Column II).$$\begin{array} {lll} \textbf{Column I} & & \textbf{Column II} \\ \text{...

Which of the following are CORRECT about protein structure?Secondary structure is formed by a repeating pattern of interactions among the polypeptide backbone atomsTertia...

The enzymes involved in ubiquitinylation of cell-cycle proteins are$\text{E}_{1}$ and $\text{E}_{2}$ Only$\text{E}_{1}$ and $\text{E}_{3}$ Only$\text{E}_{1}$ and $\text{E...

The maximum parsimony method is used to construct a phylogenetic tree for a set of sequences. Which one of the following statements about the method is $\text{CORRECT}?$I...