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Cholera toxin increases $cAMP$ levels bymodifying $G_i$ proteinmodifying $G_s$ proteinbinding to adenylate cyclaseactivating $cAMP$ phosphodiesterase
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Triose phosphate isomerase converts dihydroxy acetone phosphate $(DHAP)$ to glyceraldehyde-3-phosphate $(G-3-P)$ in a reversible reaction. At $\text{298 K and pH 7.0,}$ t...
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The plasmid DNA was subjected to restriction digestion using the enzyme $\textit{EcoRI}$ and analysed on an agarose gel. Assuming digestion has worked (the enzyme was act...
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In a relatively large but finite and closed population of sexually reproducing diploid organisms, the frequency of homozygous genotype PP changes from 0.40 to 0.50 and th...
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Topological Winding number of a $\text{2.0 kb}$ covalently closed circular DNA was found to be $191$ with a writhing number of $-4$. Hence, its $\text{LINKING NUMBER}$ an...
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Consider a population of $10,000$ individuals, of which $2500$ are homozygotes (PP) and $3000$ are heterozygotes (Pp) genotype. The frequency of allele p in the populatio...
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Match the following photoreceptors with their prosthetic groups and spectral specificity:$\begin{array}{|l|l|l|} \hline \textbf{Photoreceptor} & \textbf{Moiety that absor...
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Match the following plant sources with their secondary metabolites and medical uses:$\begin{array}{|l|l|l|} \hline \textbf{Source plant} & \textbf{Secondary metabolites} ...
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The pungency of mustard seeds is primarily due to secondary metabolites such as isothiocyanate and nitrile. The pungency is usually felt only when the seeds are crushed. ...
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In a mouse genome, the numbers of functional $V\alpha, J\alpha, V\beta, D\beta, J\beta$ gene segments are $\text{79, 38, 21, 2 and 11,}$ respectively. The total number of...
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The percentage $\text{SIMILARITIES and IDENTITIES,}$ respectively, between the two peptide sequences given below will be ____________ $\%$ and ____________ $\%$Peptide I ...
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In an affine gap penalty model, if the gap opening penalty $-20$, gap extension penalty is $-4$ and gap length is $8$, the gap score is__________.
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For their efficient translation, eubacterial $mRNAs$ possess a Shine-Dalgarno sequence for its recognition by an anti-Shine-Dalgarno sequence $(ASD)$ in the ribosomes. Th...
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Match the items in $\text{Group I}$ with $\text{Group II}$$\begin{array}{|l|l|l|l|} \hline & \text{Group I} & & \text{Group II} \\ \hline P. & \text{Receptor tyrosine kin...
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Match the immunoglobulin class in $\text{Group I}$ with its properties in $\text{Group II}$$\begin{array}{|l|l|l|l|} \hline & \textbf{Group I} && \textbf{Group II} \\ \hl...
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In a genetic cross between the genotypes $WWXX$ and $\text{wwxx}$, the following phenotypic distributions were observed among the $F_2$ progeny: $\text{WX, 562; wx, 158; ...
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The length of the minimum unique stretch of DNA sequence that can be found only once in a $3$ billion base pairs long genome is$14$$15$$16$$18$
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Lysine is being produced in a lab-scale reactor by a threonine auxotroph. After 2 weeks of operation it was observed that the concentration of lysine in the reactor was g...
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If a plant is shifted to cold temperature, which of the following changes would take place in its membrane?Ratio of unsaturated to saturated fatty acids would increaseRat...
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If protoplasts are placed in distilled water, they swell and burst as a result of endosmosis.The plot representing the kinetics of burst is
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Which of the following statements with respect to the orientation of the nitrogenous bases to the pentose sugars, and the puckering of the sugar, is correct?Anti, and 2’-...
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A dioecious plant has $XX$ sexual genotype for female and $XY$ for male. After double fertilization, what would be the genotype of the embryos and endosperms?$100\%$ ovul...
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The amino acid substitution matrices in decreasing order of stringency for comparing protein sequences arePAM$250$, PAM$120$, PAM$100$PAM$100$, PAM$120$, PAN$250$PAM$250$...
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The active site in the alpha/beta barrel structures is usually locatedinside the barrelat the amino side of the strandsat the carboxy side of the strandsat any arbitrary ...
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In a factory, two machines $M1$ and $M2$ manufacture $60\%$ and $40\%$ of the autocomponents respectively. Out of the total production $2\%$ of $M1$ and $3\%$ of $M2$ are...
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Following table gives data on tourists from different countries visiting India in the year $2011$.$$\begin{array}{|c|c|} \hline \textbf{Country} & \textbf{Number of Touri...
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If $\text{|-2X + 9| = 3}$ then the possible value of $|-X|-X^2$ would be:$30$$-30$$-42$$42$
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All professors are researchers.Some scientists are professors.Which of the given conclusions is logically valid and is inferred from the above arguments:All scientists ar...
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What is the holding period (min) at a $K$ value of $\text{3.36min}^{-1}?$$10.6$$9.5$$8.4$$7.2$
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$\text{If}$ $3 \le X \le 5 \text{ and } 8 \le Y \le 11 \text{ then which of the following options is TRUE?}$$\frac{3}{5} \le \frac{X}{Y} \le \frac{8}{5}$$\frac{3}{11} \le...
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The Headmaster ____________ to speak to you.Which of the following options is incorrect to complete the above sentence?is wantingwantswantwas wanting
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Mahatama Gandhi was known for his humility ashe played an important role in humiliating exit of British from Indiahe worked for humanitarian causeshe displayed modesty in...
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$\underset{I}{\underline{\text{All engineering students}}}\; \underset{II}{\underline{\text{should learn mechanics,}}} \;\underset{III}{\underline{\text{mathematics and}}...
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Select the pair that best expresses a relationship similar to that expressed in the pair$\text{water: pipe::}$$\text{cart: road}$$\text{electricity: wire}$$\text{sea: bea...
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Velocity of an object fired directly in upward direction is given by $V = 80-32 t$, where $t$ (time)is in seconds. When will the velocity be between $32 m/sec$ and $64 m/...
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A solution was prepared by dissolving $\text{100 mg}$ of protein $X$ in $\text{100 ml}$ of water. Molecular weight of protein $X$ is $\text{15,000 Da};$ Avogadro’s number...
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Common Data for Questions 50 and 51:The binding eciency of three diamt receptorsRL R2 and R3 were tested against a ligand usirequilibrium dialysis, uith a constant concen...
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Which one of the receptors has the highest affinity for the ligand?$R1$$R2$$R3$$R4$
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A DNA fragment of 5000bp needs to be isolated from $E.coli$ (genome size $4\times10^3 kb$) genomic library.The minimum number of independent recombinant clones required t...
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A DNA fragment of $5000bp$ needs to be isolated from E.coli (genome size $4\times10^3kb$) genomic library.The number of clones to represent this fragment in genomic libra...