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Recent questions tagged molecular-biology-and-genetics

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GATE BT 2023 | Question: 2
Acetylcholine released by the parasympathetic nerves has which one of the following functions in the heart pacemaker cells?It binds to $\text{GPCR}$ and activates $\text{...
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GATE BT 2023 | Question: 3
Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $[\mathrm{r}]$.Assertion $[\mathrm{a}]$: In multicellular organisms, cells o...
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GATE BT 2023 | Question: 4
Determine the correctness or otherwise of the following Assertion $[\text{a}]$ and the Reason $\text{[r]}$.Assertion $\text{[a]}$: Chromosome mutations can change the str...
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GATE BT 2023 | Question: 5
C-value paradox refers tothe lack of correlation between genome size and genetic complexity of an organismthe presence of genetic sequences that propagate themselves with...
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GATE BT 2023 | Question: 7
Dendritic cells are involved in cross-presentation of antigens. Which of the following protein(s) is(are) required for cross-presentation?P. Basic leucine zipper ATF-like...
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GATE BT 2023 | Question: 10
The correct sequence of events during bacteriophage infection of a bacterial cell islanding $\rightarrow$ attachment $\rightarrow$ tail contraction $\rightarrow$ penetrat...
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GATE BT 2023 | Question: 11
Intracellular proteins are targeted for proteolytic degradation in proteasomes upon conjugation with ubiquitinintegrinpeptidasecalreticulin
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GATE BT 2023 | Question: 14
Which of the following methods are used for detection of DNA and RNA, respectively?Southern and Northern blotting Southern and Western blottingNorthern and Southern blott...
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GATE BT 2023 | Question: 15
Match the types of RNA in Group I with their corresponding function in Group II.Group IGroup IIP. mRNA1. Serves as adaptors between mRNA and amino acids during protein sy...
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GATE BT 2023 | Question: 20
Fabry disease in humans is a X-linked disease. The probability (in percentage) for a phenotypically normal father and a carrier mother to have a son with Fabry disease is...
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GATE BT 2023 | Question: 28
Match the virus in Group I with the type of genome it contains in Group II.Group IGroup IIP. T4 bacteriophage1. dsRNAQ. SARS-CoV-22. ssDNAR. Pseudomonas phage $\phi 6$3. ...
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GATE BT 2023 | Question: 29
The event(s) that lead(s) to inactivation of tumor suppressor genes in cancer cells is(are)gene amplificationpromoter methylationloss of heterozygosityhistone acetylation
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GATE BT 2023 | Question: 30
Methylation of $\mathrm{CpG}$ islands near the promoter of a gene can inhibit transcription bypreventing RNA polymerase bindingfacilitating repressor bindingfacilitating ...
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GATE BT 2023 | Question: 31
Which of the following statement(s) is(are) TRUE about induced pluripotent stem cells?They can self-renewThey require specific signals to maintain their stemnessThey cann...
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GATE BT 2023 | Question: 32
Which of the following statement(s) is(are) TRUE about fluoroquinolone drugs?They contain quinolone ring(s)They inhibit RNA polymeraseThey bind to bacterial topoisomerase...
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GATE BT 2023 | Question: 34
Direct DNA transfer method(s) used for plant genetic engineering is(are)microparticle bombardmentelectroporationpolyethylene glycol treatmentAgrobacterium-mediated transf...
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GATE BT 2023 | Question: 35
Which of the following vector(s) is(are) used to clone a DNA fragment of size $220 \mathrm{~kb}$?Bacterial artificial chromosomeYeast artificial chromosomeCosmids$\text{p...
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GATE BT 2023 | Question: 45
DNA sample collected from an unidentified bacterial species $(Y)$ contains $13 \%$ of adenine. The $G+C$ content (in percentage) of $Y$ is ____________.
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GATE BT 2023 | Question: 55
A dNTP master-mix is prepared by combining $40 \mu L$ of each $20 \mathrm{mM}$ dNTP stock (dATP, dCTP, dGTP and dTTP). $4 \mu L$ of this dNTP master-mix is added to a PCR...
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GATE BT 2022 | Question: 8
The type of nucleic acid present in $\lambda$-phage isDouble stranded $\text{DNA}$Single stranded circular $\text{DNA}$Single stranded $\text{DNA}$Single stranded $\text{...
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GATE BT 2022 | Question: 11
In animal cells, the endogenously produced $\text{miRNAs}$ silence gene expression bybase pairing with the $3’$-untranslated region of specific $\text{mRNAs}$blocking $\t...
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GATE BT 2022 | Question: 14
Which of the following is $\text{NOT}$ used for generating an optimal alignment of two nucleotide sequences?Gap penaltiesMatch scoresMismatch scoresNucleotide composition
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GATE BT 2022 | Question: 15
The recognition sequences of four Type-II restriction enzymes $\text{(RE)}$ are given below. The symbol $(\downarrow)$ indicates the cleavage site. Identify the $\text{RE...
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GATE BT 2022 | Question: 16
Among individuals in a human population, minor variations exist in nucleotide sequences of chromosomes. These variations can lead to gain or loss of sites for specific re...
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GATE BT 2022 | Question: 26
Which of the following conditions will contribute to the stability of a gene pool in a natural population?Large populationNo net mutationNon-random matingNo selection $...
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GATE BT 2022 | Question: 32
Which of the following are CORRECT about protein structure?Secondary structure is formed by a repeating pattern of interactions among the polypeptide backbone atomsTertia...
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GATE BT 2022 | Question: 33
The enzymes involved in ubiquitinylation of cell-cycle proteins are$\text{E}_{1}$ and $\text{E}_{2}$ Only$\text{E}_{1}$ and $\text{E}_{3}$ Only$\text{E}_{1}$ and $\text{E...
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GATE BT 2022 | Question: 34
The maximum parsimony method is used to construct a phylogenetic tree for a set of sequences. Which one of the following statements about the method is $\text{CORRECT}?$I...
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GATE BT 2022 | Question: 36
Adenine can undergo a spontaneous change to hypoxanthine in a cell, leading to a $\text{DNA}$ base pair mismatch. The $\text{CORRECT}$ combination of enzymes that are inv...
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GATE BT 2022 | Question: 42
Emerging viruses such as $\text{SARS-Co V2}$ cause epidemics. Which of the following process(es) contribute to the rise of such viruses?Mutation of existing virusJumping ...
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GATE BT 2022 | Question: 43
Introduction of foreign genes into plant cells can be carried out usingAgrobacterium$\text{Cacl}_{2}$ mediated plasmid uptakeElectroporationGene gun
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GATE BT 2022 | Question: 44
Which of the following statement(s) regarding trafficking in eukaryotic cells is(are) CORRECT?Dynamic binds $\text{GTP}$ and is involved in vesicle buddingDynamic is invo...
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GATE BT 2022 | Question: 54
A circular plasmid has three different but unique restriction sites for enzymes $‘\text{a'}, ‘\text{b'}$ and $‘\text{c'}.$ When enzymes $‘\text{a'}$ and $‘\text{b'}$ are ...
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GATE BT 2021 | Question: 1
Coronavirus genome consists ofdouble-stranded $\text{DNA}$double-stranded $\text{RNA}$negative-sense single-stranded $\text{RNA}$positive-sense single-stranded $\text{RNA...
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GATE BT 2021 | Question: 2
The enzyme that transcribes the eukaryotic genes encoding precursor ribosomal $\text{RNAs}\; (\text{pre-RNAs}$) of $28S$, $18S$ and $5.8S$ $\text{rRNA}$s is$\text{RNA}$ p...
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GATE BT 2021 | Question: 6
The order of genes present in a chromosome is as followsWhich one of the following rearrangements represents a paracentric inversion?
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GATE BT 2021 | Question: 7
Which one of the following statements is $\text{INCORRECT}$ about hybridoma production?Hybridoma cella can use hypoxanthine and thymidine$\text{DNA}$ synthesis in myeloma...
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GATE BT 2021 | Question: 11
$\text{CRISPR-Cas}$ system is associated withadaptive immunity in eukaryotesadaptive immunity in prokaryotesinnate immunity in eukaryotesinnate immunity in prokaryotes
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GATE BT 2021 | Question: 15
The enzyme which adds phosphate group to the free $5’$ terminus of a $\text{DNA}$ sequence isadenosine kinasealkaline phosphatasepolynucleotide kinaseterminal deoxynucleo...
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GATE BT 2021 | Question: 17
The cellular process which utilizes $\text{RNA}$-induced silencing complex to block gene expression is$\text{RNA}$ editing$\text{RNA}$ interference$\text{RNA}$ polyadenyl...
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